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Experimental Preclinical Biology
  

 

Pharmacology and Toxicology (molecular & phenotypic endpoints) – Mechanism of Action (MOA) and Weight of Evidence (WOE): in-silico, in-vitro, in-vivo, ex-vivo experiments, and Clinical trials (Human & Veterinary).

Vittarthaa’s scientific and technical team has the expertise to perform various experimental procedures for Assay Development for both in-vivo, ex-vivo & in-vivo for Drug and New Product Discovery programs. Our teams are experienced in conducting a wide variety of procedures involving complex technical skills for achieve project objectives successfully with respect to the delivery of repeatable, quality data and on-time performance. We have robust, efficient processes and quality systems in place for handling a variety of samples and on-time delivery of reports. Exploratory studies for Target-validation/Pharmacology/ADME/DMPK/Toxicology studies are conducted using advanced technological platforms in various combinations. Our approach is for early detection of new indication or safety issues. Our approach to such objectives revolves around approaches that are required to fully characterize on-target and off-target effects for its Mechanisms of Action and Weight of Evidence. All early Discovery and Development programs are conducted considering the 4Rs (Reduce, Refine, Replace and Rehabilitate). We use suitable research models that are most appropriate to study the MOA & WOE.